Sunday, September 14, 2014

Why Does Diabetes Increase The Likelihood Of Heart Disease?

Glycation and Heart Disease

"Glycation is the process of bonding of proteins and lipids with sugar molecules, including glucose and fructose. This process is not enzyme controlled and is very detrimental to the human body. Latest studies have confirmed that fructose shows ten times the glycation activity of glucose......... Thus, fructose is not as harmless as scientists previously thought."

This seems to suggest that eating a lot of fruit is not such a good idea. I eat about four fruit exchanges per day, maybe I should cut back to only one fruit exchange each day. What do you think about this article?

Monday, September 1, 2014

William Rounds, 85 Years With Type 1

William Rounds was born in 1923, and diagnosed later that year, when
he was 11 months old. He was a Joslin medalist and attended the
medalist meeting in 2009. I did not attend that year, but I did attend
in 2011. He was type 1 for 85 years in 2009. The link below gives an
article about him. On the link page you will find the stories of 11
long term type 1 diabetics. The ADA magazine, the Diabetes Forecast,
celebrated their 60'th anniversary in Oct, 2008. The magazine wanted
to publish stories about people who had lived 60 years with type 1. If
you scroll down the page you will find my story in the left hand
column. William Rounds was on the cover of that issue.

Saturday, August 23, 2014

FDA Approves Human Trials, Islet Replacement

FDA approves clinical trials for "..... type 1 diabetes (T1D) encapsulated cell replacement therapy called VC-01™. The company plans to immediately initiate the first ever clinical evaluation of a stem cell-derived islet replacement therapy for the treatment of people with T1D. The trial will enroll approximately 40 people at multiple clinical sites."

Monday, August 18, 2014

I Thought I Was Cured!!! HaHa!

On Saturday I forgot to bolus at breakfast. Two hours later I discovered my mistake, and thought I would have a high. I had a meal of 31 carbs, and should have bolused 3 units. My test before breakfast was 94, and two hours later it was 89, so I still did not bolus. My pump showed that I had not bolused, and there was no insulin on board. Seeing my BG drop without a bolus was very strange, and it has never happened before. I did not need insulin, and I thought I might do the Snoopy dance, climb up on the roof, and yell "I'm cured"!!! I restrained myself, and waited for lunch.

Before lunch my test was 82, and I bolused 4.2 units for a 42 carb meal. Two hours after lunch my test was 72. I had a snack at 3 PM, The test was 110 before the snack, and 69 two hours after the snack. Sunday was very similar, but I did remember to bolus at every meal. Before breakfast my test was 88, and I bolused 3 units for a 35 carb meal. Two hours later my test was 43. I guess I should not have bolused at that breakfast either.

I have no explanation for any of these strange happenings, but I am testing frequently. Today (Monday) testing is much more normal, so I guess my "cure" was only temporary. HA!

The Joslin Medalist Study has shown that there are many long term medalists who still produce some insulin after 50+ years of type 1. One lady does occasionally produce enough insulin that she reduces her insulin dosages a lot, and sometimes does not need any insulin at all. These episodes are temporary for her, and she eventually needs full dosages again. I doubt that I would suddenly have some insulin production after 68 years of type 1, but these strange occurrences certainly do make me wonder!!!

Wednesday, August 13, 2014

Seizures With Diabetes

In the Facebook Joslin medalist group someone asked if any of us had experienced seizures due to low blood sugar. Every medalist had been type 1 for at least 50 years, and most of the 53 replies given indicated there had been no seizures. Only a few said they had experienced seizures. 

I always thought that a low that caused unconsciousness, with difficulty in being revived, was a seizure. Some medalists were saying that unconsciousness with a low is not a seizure, even if glucagon or a trip to the ER is involved. I began thinking I did not know the true definition of "seizure".

How do you define a seizure? I found the following definition of seizure on Google:

"Seizure: Uncontrolled electrical activity in the brain, which may produce a physical convulsion, minor physical signs, thought disturbances, or a combination of symptoms.The type of symptoms and seizures depend on where the abnormal electrical activity takes place in the brain, what its cause is, and such factors as the patient's age and general state of health.

Seizures can be caused by head injuries, brain tumors, lead poisoning, maldevelopment of the brain, genetic and infectious illnesses, and fevers. In fully half of the patients with seizures, no cause can yet be found."

One medalist said she had many seizures when she was very young. She fought and bit her tongue, and lost part of her tongue with the biting. A few medalists have had seizures with terrible convulsions. Most medalists have not had seizures in light of the definition given.

During my first 60 years with type 1, I had at least 200 episodes with unconsciousness and difficulty in being revived, but I never had convulsions or needed to be restrained, so I conclude that I have never had a seizure. After starting pumping in 2007, I have not needed assistance with a low.

Have any of you reading this post had seizures? If so, were they long ago, or do you still have them? This may be a very personal question, so I understand if you do not want to reply.